The emerging role of MCPH1/BRIT1 in carcinogenesis

The emerging role of MCPH1/BRIT1 in carcinogenesis

The MCPH1 gene, also known as BRCT-repeat inhibitor of hTERT expression (BRIT1), has three BRCA1 carboxyl-terminal domains which is an important regulator of DNA repair, cell cycle checkpoints and chromosome condensation. MCPH1/BRIT1 is also known as a tumour suppressor in different types of human c...

Full description

Bibliographic Details
Main Authors: Mona Alsolami, Doaa Aboalola, Dolal Malibari, Tariq Alghamdi, Walaa Alshekhi, Hind Jad, Rea Rumbold-Hall, Ahlam S. Altowairqi, Sandra M. Bell, Rawiah Abdullah Alsiary
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
MCPH1
microcephalin
BRIT1
cancer
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1047588/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1047588/full

Similar Items