Cryo-EM structure of the polycystin 2-l1 ion channel

Cryo-EM structure of the polycystin 2-l1 ion channel

We report the near atomic resolution (3.3 Å) of the human polycystic kidney disease 2-like 1 (polycystin 2-l1) ion channel. Encoded by PKD2L1, polycystin 2-l1 is a calcium and monovalent cation-permeant ion channel in primary cilia and plasma membranes. The related primary cilium-specific polycystin...

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Bibliographic Details
Main Authors: Raymond E Hulse, Zongli Li, Rick K Huang, Jin Zhang, David E Clapham
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
PC-2L1
calcium
TRP channel
cryo-EM
primary cilia
Online Access:https://elifesciences.org/articles/36931

Internet

https://elifesciences.org/articles/36931

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