Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites

Abstract Background Plasmodium falciparum (Pf) sporozoite (SPZ) vaccines are the only candidate malaria vaccines that induce > 90% vaccine efficacy (VE) against controlled human malaria infection and the only malaria vaccines to have achieved reproducible VE against malaria in adults in Africa. T...

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Bibliographic Details
Main Authors: Sumana Chakravarty, Melanie J. Shears, Eric R. James, Urvashi Rai, Natasha KC, Solomon Conteh, Lynn E. Lambert, Patrick E. Duffy, Sean C. Murphy, Stephen L. Hoffman
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Malaria Journal
Online Access:https://doi.org/10.1186/s12936-022-04261-z