Synthesis and <i>h</i>LDH Inhibitory Activity of Analogues to Natural Products with 2,8-Dioxabicyclo[3.3.1]nonane Scaffold
Human lactate dehydrogenase (<i>h</i>LDH) is a tetrameric enzyme present in almost all tissues. Among its five different isoforms, <i>h</i>LDHA and <i>h</i>LDHB are the predominant ones. In the last few years, <i>h</i>LDHA has emerged as a therapeutic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/12/9925 |