Shared and Differential Retinal Responses against Optic Nerve Injury and Ocular Hypertension

Shared and Differential Retinal Responses against Optic Nerve Injury and Ocular Hypertension

Glaucoma, one of the leading causes of blindness worldwide, affects primarily retinal ganglion cells (RGCs) and their axons. The pathophysiology of glaucoma is not fully understood, but it is currently believed that damage to RGC axons at the optic nerve head plays a major role. Rodent models to stu...

Full description

Bibliographic Details
Main Authors: Manuel Vidal-Sanz, Caridad Galindo-Romero, Francisco J. Valiente-Soriano, Francisco M. Nadal-Nicolás, Arturo Ortin-Martinez, Giuseppe Rovere, Manuel Salinas-Navarro, Fernando Lucas-Ruiz, Maria C. Sanchez-Migallon, Paloma Sobrado-Calvo, Marcelino Aviles-Trigueros, María P. Villegas-Pérez, Marta Agudo-Barriuso
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Neuroscience
Subjects:
glaucoma
chronic ocular hypertension
acute ocular hypertension
axotomy
Brn3a retinal ganglion cells
melanopsin retinal ganglion cells
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00235/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00235/full

Similar Items