LINC00673 Represses CDKN2C and Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells by EZH2-Mediated H3K27 Trimethylation

LINC00673 Represses CDKN2C and Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells by EZH2-Mediated H3K27 Trimethylation

Long non-coding RNAs (lncRNAs), some of the most abundant epigenetic regulators, play an important role in esophageal squamous cell carcinoma (ESCC). In the current study, the functions and mechanisms of the lncRNA LINC00673 were investigated. The expression levels of LINC00673 and its potential tar...

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Bibliographic Details
Main Authors: Menghan Zhou, Yuhang Mao, Shenling Yu, Yiping Li, Rong Yin, Qin Zhang, Tianyu Lu, Rui Sun, Shaofeng Lin, Yanyan Qian, Ying Xu, Hong Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
ESCC
LINC00673
CDKN2C
H3K27me3
cell cycle
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01546/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01546/full

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