Effect of intrathecal glycine and related amino acids on the allodynia and hyperalgesic action of strychnine or bicuculline in mice

BackgroundThe intrathecal (IT) administration of glycine or GABAA receptor antagonist result in a touch evoked allodynia through disinhibition in the spinal cord. Glycine is an inhibitory neurotransmitter that appears to be important in sensory processing in the spinal cord. This study was aimed to...

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Bibliographic Details
Main Authors: Eui Sung Lim, Il Ok Lee
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2010-01-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kjae-58-76.pdf