Induction of Apoptosis by 11-Dehydrosinulariolide via Mitochondrial Dysregulation and ER Stress Pathways in Human Melanoma Cells

Induction of Apoptosis by 11-Dehydrosinulariolide via Mitochondrial Dysregulation and ER Stress Pathways in Human Melanoma Cells

In this study the isolated compound 11-dehydrosinulariolide from soft coral<em> Sinularia </em><em>leptoclados </em>possessed anti-proliferative, anti-migratory and apoptosis-inducing activities against A2058 melanoma cells. Anti-tumor effects...

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Bibliographic Details
Main Authors: Jeff Yi-Fu Chen, Bing-Sang Wong, Ya-Ting Yang, Jui-Hsin Su, Chien-Chih Chiu, Han Hsiang Huang, Feng-Jen Tsai, Jen-Jie Lin, Yu-Jen Wu, Tzu-Rong Su
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Marine Drugs
Subjects:
melanoma
11-dehydrosinulariolide
mitochondrial dysregulation
ER stress
Online Access:http://www.mdpi.com/1660-3397/10/8/1883

Internet

http://www.mdpi.com/1660-3397/10/8/1883

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