Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships

Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships

Abstract Background Heritability and genetic correlation can be estimated from genome-wide single-nucleotide polymorphism (SNP) data using various methods. We recently developed multivariate genomic-relatedness-based restricted maximum likelihood (MGREML) for statistically and computationally effici...

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Bibliographic Details
Main Authors: Ronald De Vlaming, Eric A. W. Slob, Patrick J. F. Groenen, Cornelius A. Rietveld
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Bioinformatics
Subjects:
SNP heritability
Genetic correlation
GREML
Genetic factor model
Genomic SEM
Online Access:https://doi.org/10.1186/s12859-022-04835-3

Internet

https://doi.org/10.1186/s12859-022-04835-3

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