Advances in the treatment of advanced melanoma with NRAS gene mutation

Oncogenic mutations are responsible for a majority of the malignancy of melanoma. Activating mutations of NRAS gene are found in 15%-20% melanoma cases, endowing the tumor cells with more aggressive phenotypes and greater difficulty to treat. The development of targeted inhibitor of mutant NRAS rema...

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Bibliographic Details
Main Author: ZHAO Bolun, ZHU Guannan
Format: Article
Language:English
Published: Editorial Office of China Oncology 2023-10-01
Series:Zhongguo aizheng zazhi
Subjects:
Online Access:http://www.china-oncology.com/fileup/1007-3639/PDF/1698723448742-951764022.pdf