Presynaptic NMDARs cooperate with local spikes toward GABA release from the reciprocal olfactory bulb granule cell spine

Presynaptic NMDARs cooperate with local spikes toward GABA release from the reciprocal olfactory bulb granule cell spine

In the rodent olfactory bulb the smooth dendrites of the principal glutamatergic mitral cells (MCs) form reciprocal dendrodendritic synapses with large spines on GABAergic granule cells (GC), where unitary release of glutamate can trigger postsynaptic local activation of voltage-gated Na+-channels (...

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Bibliographic Details
Main Authors: Vanessa Lage-Rupprecht, Li Zhou, Gaia Bianchini, S Sara Aghvami, Max Mueller, Balázs Rózsa, Marco Sassoè-Pognetto, Veronica Egger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
olfactory bulb
reciprocal synapse
presynaptic NMDA receptor
mitral cell
granule cell
Online Access:https://elifesciences.org/articles/63737

Internet

https://elifesciences.org/articles/63737

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