Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals

Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals

ABSTRACT SARS-CoV-2 anti-spike antibody concentrations and angiotensin converting enzyme-2 (ACE-2) inhibition have been used as surrogates to live viral neutralizing antibody titers; however, validity among vaccinated individuals is unclear. We tested the correlation of these measures among vaccinat...

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Bibliographic Details
Main Authors: Brian Grunau, Martin Prusinkiewicz, Michael Asamoah-Boaheng, Liam Golding, Pascal M. Lavoie, Martin Petric, Paul N. Levett, Scott Haig, Vilte Barakauskas, Mohammad Ehsanul Karim, Agatha N. Jassem, Steven J. Drews, Sadaf Sediqi, David M. Goldfarb
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
neutralizing antibodies
SARS-CoV-2
COVID-19
anti-spike
ACE-2
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01315-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01315-22

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