Screening and Evaluation of Novel Compounds against Hepatitis B Virus Polymerase Using Highly Purified Reverse Transcriptase Domain

Hepatitis B virus (HBV) polymerase seems to be very hard to express and purify sufficiently, which has long hampered the generation of anti-HBV drugs based on the nature of the polymerase. To date, there has been no useful system developed for drug screening against HBV polymerase. In this study, we...

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Bibliographic Details
Main Authors: Eriko Ohsaki, Keiji Ueda
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/8/840