The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence [version 2; peer review: 2 approved]

TAR DNA-binding protein 43 (TDP-43) is a DNA/RNA binding protein playing a critical role in the regulation of transcription, splicing and RNA stability. Mutations in TARDBP leading to aggregation, are suspected to be a characteristic feature of various neurogenerative diseases. The lack of well-char...

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Bibliographic Details
Main Authors: Peter S. McPherson, Carl Laflamme, Kathleen Southern, Donovan Worrall, Riham Ayoubi, Maryam Fotouhi
Format: Article
Language:English
Published: F1000 Research Ltd 2023-06-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/12-277/v2