New Thiazolyl-Pyrazoline Derivatives as Potential Dual EGFR/HER2 Inhibitors: Design, Synthesis, Anticancer Activity Evaluation and In Silico Study

New Thiazolyl-Pyrazoline Derivatives as Potential Dual EGFR/HER2 Inhibitors: Design, Synthesis, Anticancer Activity Evaluation and In Silico Study

<b>A</b> new series of thiazolyl-pyrazoline derivatives (<b>4a</b>–<b>d</b>, <b>5a</b>–<b>d 6a</b>, <b>b</b>, <b>7a</b>–<b>d</b>, <b>8a</b>, <b>b</b>, and <b>10a</b>, &...

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Bibliographic Details
Main Authors: Mariam M. Fakhry, Amr A. Mattar, Marwa Alsulaimany, Ebtesam M. Al-Olayan, Sara T. Al-Rashood, Hatem A. Abdel-Aziz
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
thiazolyl-pyrazoline
anti-cancer
cell cycle
apoptosis
EGFR
HER2
Online Access:https://www.mdpi.com/1420-3049/28/21/7455

Internet

https://www.mdpi.com/1420-3049/28/21/7455

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