Global Autozygosity Is Associated with Cancer Risk, Mutational Signature and Prognosis

Global autozygosity quantifies the genome-wide levels of homozygous and heterozygous variants. It is the signature of non-random reproduction, though it can also be driven by other factors, and has been used to assess risk in various diseases. However, the association between global autozygosity and...

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Bibliographic Details
Main Authors: Limin Jiang, Fei Guo, Jijun Tang, Shuguan Leng, Scott Ness, Fei Ye, Huining Kang, David C. Samuels, Yan Guo
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/12/3646