ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres
The yeast homologs of the ATM and ATR DNA damage response kinases play key roles in telomerase-mediated telomere maintenance, but the role of ATM/ATR in the mammalian telomerase pathway has been less clear. Here, we demonstrate the requirement for ATM and ATR in the localization of telomerase to tel...
Hlavní autoři: | Adrian S. Tong, J. Lewis Stern, Agnel Sfeir, Melissa Kartawinata, Titia de Lange, Xu-Dong Zhu, Tracy M. Bryan |
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Médium: | Článek |
Jazyk: | English |
Vydáno: |
Elsevier
2015-11-01
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Edice: | Cell Reports |
On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2211124715012115 |
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