ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres

The yeast homologs of the ATM and ATR DNA damage response kinases play key roles in telomerase-mediated telomere maintenance, but the role of ATM/ATR in the mammalian telomerase pathway has been less clear. Here, we demonstrate the requirement for ATM and ATR in the localization of telomerase to tel...

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Bibliographic Details
Main Authors: Adrian S. Tong, J. Lewis Stern, Agnel Sfeir, Melissa Kartawinata, Titia de Lange, Xu-Dong Zhu, Tracy M. Bryan
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715012115

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