Pathobiological Interactions of Local Bone Marrow Renin-Angiotensin System and Central Nervous System in Systemic Arterial Hypertension

Pathobiological Interactions of Local Bone Marrow Renin-Angiotensin System and Central Nervous System in Systemic Arterial Hypertension

Circulating renin-angiotensin system (RAS) and local paracrin-autocrin-intracrin tissue-based RAS participate in numerous pathobiological events. Pro-inflammatory, pro-fibrotic, and pro-thrombotic consequences associated with local RAS activation have been detected at cellular and molecular level. R...

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Bibliographic Details
Main Authors: Rafiye Ciftciler, Ibrahim Celalettin Haznedaroglu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Endocrinology
Subjects:
renin-angiotensin system
bone marrow
atherosclerosis
hypertension
central nervous system
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00425/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00425/full

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