Simultaneous Determination of Four Tanshinones by UPLC-TQ/MS and Their Pharmacokinetic Application after Administration of Single Ethanol Extract of Danshen Combined with Water Extract in Normal and Adenine-Induced Chronic Renal Failure Rats

Simultaneous Determination of Four Tanshinones by UPLC-TQ/MS and Their Pharmacokinetic Application after Administration of Single Ethanol Extract of Danshen Combined with Water Extract in Normal and Adenine-Induced Chronic Renal Failure Rats

Salvia miltiorrhiza, one of the major traditional Chinese medicines, is commonly used and the main active ingredients—tanshinones—possess the ability to improve renal function. In this paper, the UPLC-TQ/MS method of simultaneously determining four tanshinones—tanshinone IIA, dihydrotanshinone I, ta...

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Bibliographic Details
Main Authors: Hong-Die Cai, Shu-Lan Su, Yonghui Li, Zhenhua Zhu, Jianming Guo, Yue Zhu, Sheng Guo, Dawei Qian, Jinao Duan
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
Salvia miltiorrhiza Bge.
tanshinones
pharmacokinetics
UPLC-TQ/MS
chronic renal failure
Online Access:http://www.mdpi.com/1420-3049/21/12/1630

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http://www.mdpi.com/1420-3049/21/12/1630

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