Empagliflozin protects against renal ischemia/reperfusion injury in mice

Abstract Renal ischemia/reperfusion (I/R) can induce acute kidney injury. Empagliflozin is a newly developed inhibitor of sodium-glucose cotransporter-2 (SGLT2) approved as an antidiabetic medication for patients with type 2 diabetes mellitus. Despite the established cardioprotective functions of em...

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Bibliographic Details
Main Authors: Qifeng Wang, Feng Ju, Jiaxue Li, Ting Liu, Yunxia Zuo, Geoffrey W. Abbott, Zhaoyang Hu
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24103-x