RNA chain length and stoichiometry govern surface tension and stability of protein-RNA condensates

Summary: Proteomic studies have shown that cellular condensates are frequently enriched in diverse RNA molecules, which is suggestive of mechanistic links between phase separation and transcriptional activities. Here, we report a systematic experimental and computational study of thermodynamic lands...

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Bibliographic Details
Main Authors: Rabia Laghmach, Ibraheem Alshareedah, Matthew Pham, Muralikrishna Raju, Priya R. Banerjee, Davit A. Potoyan
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222003753