Association of Leptin Gene DNA Methylation With Diagnosis and Treatment Outcome of Anorexia Nervosa

Association of Leptin Gene DNA Methylation With Diagnosis and Treatment Outcome of Anorexia Nervosa

Epigenetic alterations are increasingly implicated in the pathophysiology of anorexia nervosa (AN) but are as yet poorly understood. We investigated possible associations between the leptin gene (LEP) and the leptin receptor gene (LEPR) DNA promoter methylation and (1) a diagnosis of AN and (2) outc...

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Bibliographic Details
Main Authors: Alexandra Neyazi, Vanessa Buchholz, Alexandra Burkert, Thomas Hillemacher, Martina de Zwaan, Wolfgang Herzog, Kirsten Jahn, Katrin Giel, Stephan Herpertz, Christian A. Buchholz, Andreas Dinkel, Markus Burgmer, Almut Zeeck, Stefan Bleich, Stephan Zipfel, Helge Frieling
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Psychiatry
Subjects:
leptin
leptin receptor
methylation
outcome
anorexia nervosa
epigenetic
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00197/full

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https://www.frontiersin.org/article/10.3389/fpsyt.2019.00197/full

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