Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses

Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses

The subunit composition of synaptic NMDA receptors (NMDAR), such as the relative content of GluN2A- and GluN2B-containing receptors, greatly influences the glutamate synaptic transmission. Receptor co-agonists, glycine and D-serine, have intriguingly emerged as potential regulators of the receptor t...

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Bibliographic Details
Main Authors: Joana S Ferreira, Thomas Papouin, Laurent Ladépêche, Andrea Yao, Valentin C Langlais, Delphine Bouchet, Jérôme Dulong, Jean-Pierre Mothet, Silvia Sacchi, Loredano Pollegioni, Pierre Paoletti, Stéphane Henri Richard Oliet, Laurent Groc
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
NMDA
subunit trafficking
synapse
Online Access:https://elifesciences.org/articles/25492

Internet

https://elifesciences.org/articles/25492

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