Role of the route of leukotrienes in an experimental model of oral mucositis induced by 5-fluorouracil

Role of the route of leukotrienes in an experimental model of oral mucositis induced by 5-fluorouracil

Abstract Purpose: To investigate the participation of cysteinyl leukotrienes in the pathophysiology of oral mucositis. Methods: Oral mucositis was induced in hamsters using 5-fluorouracil (5-FU; 60 and 40 mg/kg; i.p., on days 1 and 2, respectively, and with excoriations in jugal mucosa on day 4)....

Full description

Bibliographic Details
Main Authors: Viviane Carvalho da Silva, Renata Ferreira de Carvalho Leitão, Gerly Anne de Castro Brito, Conceição da Silva Martins, Gildenio Estevam Freire, Karoline Saboia Aragão, Carlos Wagner de Souza Wanderley, Marcos Rabelo de Freitas
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2017-09-01
Series:Acta Cirúrgica Brasileira
Subjects:
Arachidonate 5-Lipoxygenase
Stomatitis
Fluorouracil
Cricetinae
Online Access:http://www.scielo.br/pdf/acb/v32n9/1678-2674-acb-32-09-00712.pdf

Internet

http://www.scielo.br/pdf/acb/v32n9/1678-2674-acb-32-09-00712.pdf

Similar Items