Modeling HIV-1 Within-Host Dynamics After Passive Infusion of the Broadly Neutralizing Antibody VRC01

VRC01 is a broadly neutralizing antibody that targets the CD4 binding site of HIV-1 gp120. Passive administration of VRC01 in humans has assessed the safety and the effect on plasma viremia of this monoclonal antibody (mAb) in a phase 1 clinical trial. After VRC01 infusion, the plasma viral load in...

Cijeli opis

Bibliografski detalji
Glavni autori: E. Fabian Cardozo-Ojeda, Alan S. Perelson
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2021-08-01
Serija:Frontiers in Immunology
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2021.710012/full