Mitochondrial citrate metabolism and efflux regulate BeWo differentiation

Mitochondrial citrate metabolism and efflux regulate BeWo differentiation

Abstract Cytotrophoblasts fuse to form and renew syncytiotrophoblasts necessary to maintain placental health throughout gestation. During cytotrophoblast to syncytiotrophoblast differentiation, cells undergo regulated metabolic and transcriptional reprogramming. Mitochondria play a critical role in...

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Bibliographic Details
Main Authors: Renee M. Mahr, Snehalata Jena, Sereen K. Nashif, Alisa B. Nelson, Adam J. Rauckhorst, Ferrol I. Rome, Ryan D. Sheldon, Curtis C. Hughey, Patrycja Puchalska, Micah D. Gearhart, Eric B. Taylor, Peter A. Crawford, Sarah A. Wernimont
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34435-x

Internet

https://doi.org/10.1038/s41598-023-34435-x

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