Mitochondrial citrate metabolism and efflux regulate BeWo differentiation

Mitochondrial citrate metabolism and efflux regulate BeWo differentiation

Abstract Cytotrophoblasts fuse to form and renew syncytiotrophoblasts necessary to maintain placental health throughout gestation. During cytotrophoblast to syncytiotrophoblast differentiation, cells undergo regulated metabolic and transcriptional reprogramming. Mitochondria play a critical role in...

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Podrobná bibliografie
Hlavní autoři: Renee M. Mahr, Snehalata Jena, Sereen K. Nashif, Alisa B. Nelson, Adam J. Rauckhorst, Ferrol I. Rome, Ryan D. Sheldon, Curtis C. Hughey, Patrycja Puchalska, Micah D. Gearhart, Eric B. Taylor, Peter A. Crawford, Sarah A. Wernimont
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2023-05-01
Edice:Scientific Reports
On-line přístup:https://doi.org/10.1038/s41598-023-34435-x

Internet

https://doi.org/10.1038/s41598-023-34435-x

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