Use of almitrine in spontaneously breathing patients with COVID-19 treated with high-flow nasal cannula oxygen therapy and with persistent hypoxemia

Abstract Background Almitrine, a selective pulmonary vasoconstrictor in hypoxic area, improves oxygenation in mechanically ventilated patients with COVID-19 but its effects in spontaneously breathing patients with COVID-19 remain to be determined. Methods We prospectively studied the effects of almi...

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Bibliographic Details
Main Authors: Clément Saccheri, Lucas Morand, Marie Juston, Denis Doyen, Hervé Hyvernat, Romain Lombardi, Raphaël Devanlay, Émilie Panicucci, Jean Dellamonica, Mathieu Jozwiak
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-022-02308-y