Counselling Framework for Germline <i>BRCA1/2</i> and <i>PALB2</i> Carriers Considering Risk-Reducing Mastectomy

Counselling Framework for Germline <i>BRCA1/2</i> and <i>PALB2</i> Carriers Considering Risk-Reducing Mastectomy

Female <i>BRCA1/2</i> and <i>PALB2</i> germline pathogenic variant carriers have an increased lifetime risk of breast cancer and may wish to consider risk-reducing mastectomy (RRM) for surgical prevention. Quantifying the residual lifetime risk and absolute benefit from RRM r...

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Bibliographic Details
Main Authors: Stephanie M. Wong, Carla Apostolova, Elisheva Eisenberg, William D. Foulkes
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Current Oncology
Subjects:
breast neoplasms
<i>BRCA1</i>
<i>BRCA2</i>
hereditary breast and ovarian cancer syndrome
mastectomy
cancer prevention
Online Access:https://www.mdpi.com/1718-7729/31/1/23

Internet

https://www.mdpi.com/1718-7729/31/1/23

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