Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules

Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules

Summary: Phosphopeptides presented by major histocompatibility complex (MHC) class I have been regarded as a pivotal type of cancer neoantigens that are recognized by T cells. The structural basis of single-phosphorylated peptide presentation has been well studied. Diphosphorylation with one interva...

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Bibliographic Details
Main Authors: Yingze Zhao, Mingwei Sun, Nan Zhang, Xueyuan Liu, Can Yue, Lei Feng, Shushen Ji, Xiao Liu, Jianxun Qi, Catherine C.L. Wong, George F. Gao, William J. Liu
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Biomolecules
Peptides
Immunology
Crystallography
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222002838

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http://www.sciencedirect.com/science/article/pii/S2589004222002838

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