Metabolic profiling reveals metabolic features of consolidation therapy in pediatric acute lymphoblastic leukemia

Metabolic profiling reveals metabolic features of consolidation therapy in pediatric acute lymphoblastic leukemia

Abstract Acute lymphoblastic leukemia (ALL) and its treatment continue to pose substantial risks. To understand ALL more deeply, the metabolome in fasting plasma of 27 ALL patients before and after high-dose methotrexate therapies (consolidation therapy) including methotrexate and 6-mercaptopurine (...

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Bibliographic Details
Main Authors: Jinqiu Fu, Aijun Zhang, Qinqin Liu, Dong Li, Xiaoming Wang, Libo Si
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Cancer & Metabolism
Subjects:
Metabolomics
Acute lymphoblastic leukemia
Consolidation therapy
Online Access:https://doi.org/10.1186/s40170-023-00302-6

Internet

https://doi.org/10.1186/s40170-023-00302-6

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