The Notch1 signaling pathway directly modulates the human RANKL-induced osteoclastogenesis

The Notch1 signaling pathway directly modulates the human RANKL-induced osteoclastogenesis

Abstract Notch signaling is an evolutionary conserved pathway with a key role in tissue homeostasis, differentiation and proliferation. It was reported that Notch1 receptor negatively regulates mouse osteoclast development and formation by inhibiting the expression of macrophage colony-stimulating f...

Full description

Bibliographic Details
Main Authors: Costanzo Padovano, Salvatore Daniele Bianco, Francesca Sansico, Elisabetta De Santis, Francesco Tamiro, Mattia Colucci, Beatrice Totti, Serena Di Iasio, Gaja Bruno, Patrizio Panelli, Giuseppe Miscio, Tommaso Mazza, Vincenzo Giambra
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48615-2

Internet

https://doi.org/10.1038/s41598-023-48615-2

Similar Items