Quantitative structured illumination microscopy via a physical model-based background filtering algorithm reveals actin dynamics

Abstract Despite the prevalence of superresolution (SR) microscopy, quantitative live-cell SR imaging that maintains the completeness of delicate structures and the linearity of fluorescence signals remains an uncharted territory. Structured illumination microscopy (SIM) is the ideal tool for live-c...

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Bibliographic Details
Main Authors: Yanquan Mo, Kunhao Wang, Liuju Li, Shijia Xing, Shouhua Ye, Jiayuan Wen, Xinxin Duan, Ziying Luo, Wen Gou, Tongsheng Chen, Yu-Hui Zhang, Changliang Guo, Junchao Fan, Liangyi Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38808-8