Ginsenoside Rg1 attenuates the NASH phenotype by regulating the miR-375-3p/ATG2B/PTEN-AKT axis to mediate autophagy and pyroptosis

Ginsenoside Rg1 attenuates the NASH phenotype by regulating the miR-375-3p/ATG2B/PTEN-AKT axis to mediate autophagy and pyroptosis

Abstract Background Nonalcoholic steatohepatitis (NASH) is one of the most frequent liver diseases at present, and there is no radical treatment. The consequences of a variety of ginsenoside compounds on this situation have before been reported, however, the specific effect on the monomeric ginsenos...

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Bibliographic Details
Main Authors: Xuanxin Chen, Wei Xue, Jia Zhang, Jiayi Peng, Wenxiang Huang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Lipids in Health and Disease
Subjects:
NASH
Ginsenoside Rg1
miR-375-3p
ATG2B
Autophagy
Pyroptosis
Online Access:https://doi.org/10.1186/s12944-023-01787-2

Internet

https://doi.org/10.1186/s12944-023-01787-2

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