Targeted anatomical and functional identification of antinociceptive and pronociceptive serotonergic neurons that project to the spinal dorsal horn

Targeted anatomical and functional identification of antinociceptive and pronociceptive serotonergic neurons that project to the spinal dorsal horn

Spinally projecting serotonergic neurons play a key role in controlling pain sensitivity and can either increase or decrease nociception depending on physiological context. It is currently unknown how serotonergic neurons mediate these opposing effects. Utilizing virus-based strategies and Tph2-Cre...

Full description

Bibliographic Details
Main Authors: Robert Philip Ganley, Marilia Magalhaes de Sousa, Kira Werder, Tugce Öztürk, Raquel Mendes, Matteo Ranucci, Hendrik Wildner, Hanns Ulrich Zeilhofer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
pain
serotonin
hindbrain
projection neuron
spinal cord
Online Access:https://elifesciences.org/articles/78689

Internet

https://elifesciences.org/articles/78689

Similar Items