Characterization of four new monoclonal antibodies against the distal N-terminal region of PrPc

Prion diseases are a group of fatal neurodegenerative disorders that affect humans and animals. They are characterized by the accumulation in the central nervous system of a pathological form of the host-encoded prion protein (PrPC). The prion protein is a membrane glycoprotein that consists of two...

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Bibliographic Details
Main Authors: Alessandro Didonna, Anja Colja Venturini, Katrina Hartman, Tanja Vranac, Vladka Čurin Šerbec, Giuseppe Legname
Format: Article
Language:English
Published: PeerJ Inc. 2015-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/811.pdf