mTOR activity is essential for retinal pigment epithelium regeneration in zebrafish.

The retinal pigment epithelium (RPE) plays numerous critical roles in maintaining vision and this is underscored by the prevalence of degenerative blinding diseases like age-related macular degeneration (AMD), in which visual impairment is caused by progressive loss of RPE cells. In contrast to mamm...

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Bibliographic Details
Main Authors: Fangfang Lu, Lyndsay L Leach, Jeffrey M Gross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009628