Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking

Amidation of glutamate residues in mycobacterial peptidoglycan is essential for cell wall cross-linking

IntroductionMycobacteria assemble a complex cell wall with cross-linked peptidoglycan (PG) which plays an essential role in maintenance of cell wall integrity and tolerance to osmotic pressure. We previously demonstrated that various hydrolytic enzymes are required to remodel PG during essential pro...

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Bibliographic Details
Main Authors: Moagi T. Shaku, Karl L. Ocius, Alexis J. Apostolos, Marcos M. Pires, Michael S. VanNieuwenhze, Neeraj Dhar, Bavesh D. Kana
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
MurT-GatD complex
peptidoglycan biosynthesis
peptidoglycan amidation
peptidoglycan cross-linking
peptidoglycan remodelling
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1205829/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1205829/full

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