Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Identification of MAP3K4 as a novel regulation factor of hepatic lipid metabolism in non-alcoholic fatty liver disease

Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder with abnormal lipid metabolism. The present study was to identify regulatory genes related to lipid droplets (LDs) abnormal accumulation in NAFLD. Methods transcriptomic analysis and bioinformatics analysis (GEO da...

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Bibliographic Details
Main Authors: Zhiyong He, Yangyang Bin, Guangshun Chen, Qiang Li, Wenling Fan, Yongqiang Ma, Junfang Yi, Xiaohua Luo, Zhi Tan, Jiequn Li
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Translational Medicine
Subjects:
Non-alcoholic fatty liver disease
Lipid droplets
Transcriptomics analysis
MAP3K4
Online Access:https://doi.org/10.1186/s12967-022-03734-8

Internet

https://doi.org/10.1186/s12967-022-03734-8

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