In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene

In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene

Abstract Single nucleotide polymorphisms (SNPs) are one of the most common determinants and potential biomarkers of human disease pathogenesis. SNPs could alter amino acid residues, leading to the loss of structural and functional integrity of the encoded protein. In humans, members of the minichrom...

Full description

Bibliographic Details
Main Authors: Md. Mostafa Kamal, Md. Sohel Mia, Md. Omar Faruque, Md. Golam Rabby, Md. Numan Islam, Md. Enamul Kabir Talukder, Tanveer A. Wani, M. Atikur Rahman, Md. Mahmudul Hasan
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Scientific Reports
Subjects:
Single nucleotide polymorphisms
Missense SNPs
Pathogenicity prediction and computational tools
Online Access:https://doi.org/10.1038/s41598-024-62299-2

Internet

https://doi.org/10.1038/s41598-024-62299-2

Similar Items