Role of genome topology in the stability of viral capsids

We explore how the stability of RNA viruses depends on genome topology and interactions between RNA and the capsid proteins. RNA is modeled as a branched polymer with 12 attractive sites (packaging signals) that can form bonds with 12 icosahedrally distributed capsid sites. The genome topology is en...

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Bibliographic Details
Main Authors: James Daniel Farrell, Jure Dobnikar, Rudolf Podgornik
Format: Article
Language:English
Published: American Physical Society 2023-03-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.5.L012040