Biphasic and directed translocation of protein kinase Cα inside cultured endothelial cells before migration
Mechanical wounding of an endothelial monolayer induces an immediate Ca2+ wave. Several hours later, the denuded area is covered by endothelial cells (ECs) that migrate to the wound. This migration process is closely related to protein kinase Cα (PKCα), a Ca2+-dependent protein that translocates fro...
Main Authors: | Masataka Arai, Tomoya Shimada, Chihiro Kora, Kazuhiro Nakashima, Toshihiro Sera, Susumu Kudo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-12-01
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Series: | Biochemistry and Biophysics Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580817301425 |
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