(−)-Naringenin 4′,7-dimethyl Ether Isolated from <i>Nardostachys jatamansi</i> Relieves Pain through Inhibition of Multiple Channels

(−)-Naringenin 4′,7-dimethyl Ether Isolated from <i>Nardostachys jatamansi</i> Relieves Pain through Inhibition of Multiple Channels

(−)-Naringenin 4′,7-dimethyl ether ((−)-NRG-DM) was isolated for the first time by our lab from <i>Nardostachys jatamansi</i> DC, a traditional medicinal plant frequently used to attenuate pain in Asia. As a natural derivative of analgesic, the current study was designed to test the pote...

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Bibliographic Details
Main Authors: Ru-Rong Gu, Xian-Hua Meng, Yin Zhang, Hai-Yan Xu, Li Zhan, Zhao-Bing Gao, Jun-Li Yang, Yue-Ming Zheng
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
(−)-Naringenin 4′,7-dimethyl ether
analgesic candidate
mechanism study
delayed rectifier potassium currents
ion channels
Online Access:https://www.mdpi.com/1420-3049/27/5/1735

Internet

https://www.mdpi.com/1420-3049/27/5/1735

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