Enhanced Lymphatic Uptake of Leflunomide Loaded Nanolipid Carrier via Chylomicron Formation for the Treatment of Rheumatoid Arthritis

Enhanced Lymphatic Uptake of Leflunomide Loaded Nanolipid Carrier via Chylomicron Formation for the Treatment of Rheumatoid Arthritis

Purpose: The current study aims the lymphatic delivery of leflunomide loaded nanostructured lipid carriers (LNLC) for the treatment of rheumatoid arthritis, mainly focussed to enhance the lymphatic delivery via chylomicron formation, improved bioavailability and reduced systemic toxicity. Methods: M...

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Bibliographic Details
Main Authors: Yadhu Krishnan, Shilpa Mukundan, Suresh Akhil, Swati Gupta, Vidya Viswanad
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Rheumatoid arthritis
Lymphatic uptake
Nano lipid carriers
Leflunomide
Chylomicron
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-8-257.pdf

Internet

http://apb.tbzmed.ac.ir/PDF/apb-8-257.pdf

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