Risk Assessment of (Herbal) Teas Containing Pyrrolizidine Alkaloids (PAs) Based on Margin of Exposure Approach and Relative Potency (REP) Factors

Pyrrolizidine alkaloids (PAs) present distinct toxicity potencies depending on their metabolites and in vivo toxicokinetics. To represent the potency differences of various PAs, the interim relative potency (REP) factors have been derived. However, little is known about the risk assessment for (herb...

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Bibliographic Details
Main Authors: Lu Chen, Qian Zhang, Ziwei Yi, Yu Chen, Weihan Xiao, Dan Su, Wenbiao Shi
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/11/19/2946