Transplantation of human adipose-derived stem cells overexpressing LIF/IFN-β promotes recovery in experimental autoimmune encephalomyelitis (EAE)

Abstract Multiple Sclerosis (MS) is the most common demyelinating disease with inflammatory demyelination in the central nerve system. Besides the defect in the myelin repair process, the balance change in inflammatory and anti- inflammatory cytokines is one of the most significant factors in MS pat...

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Bibliographic Details
Main Authors: Mahdieh Yousefi, Abolghasem Nabipour, Mazdak Ganjalikhani Hakemi, Mehnoosh Ashja-Arvan, Noushin Amirpour, Hossein Salehi
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21850-9