Spores of Clostridioides difficile are toxin delivery vehicles

Spores of Clostridioides difficile are toxin delivery vehicles

Abstract Clostridioides difficile causes a wide range of intestinal diseases through the action of two main cytotoxins, TcdA and TcdB. Ingested spores germinate in the intestine establishing a population of cells that produce toxins and spores. The pathogenicity locus, PaLoc, comprises several genes...

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Main Authors: Carolina P. Cassona, Sara Ramalhete, Khira Amara, Thomas Candela, Imad Kansau, Cécile Denève-Larrazet, Claire Janoir-Jouveshomme, Luís Jaime Mota, Bruno Dupuy, Mónica Serrano, Adriano O. Henriques
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06521-x

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https://doi.org/10.1038/s42003-024-06521-x

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