Investigating causal associations among gut microbiota, metabolites, and liver diseases: a Mendelian randomization study

Investigating causal associations among gut microbiota, metabolites, and liver diseases: a Mendelian randomization study

ObjectiveThere is some evidence for an association between gut microbiota and nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD), and viral hepatitis, but no studies have explored their causal relationship.MethodsInstrumental variables of the gut microbiota (N = 13266) and gut m...

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Bibliographic Details
Main Authors: Lilong Zhang, Liuliu Zi, Tianrui Kuang, Kunpeng Wang, Zhendong Qiu, Zhongkai Wu, Li Liu, Rongqiang Liu, Peng Wang, Weixing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Endocrinology
Subjects:
alcoholic liver disease
nonalcoholic fatty liver disease
viral hepatitis
gut microbiota
gut microbiota-derived metabolites
mendelian randomization analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1159148/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1159148/full

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