Advancing deep variant phenotyping of mitochondrial enzyme complexes for precision medicine in allogeneic hematopoietic stem-cell transplantation

Advancing deep variant phenotyping of mitochondrial enzyme complexes for precision medicine in allogeneic hematopoietic stem-cell transplantation

Allogeneic hematopoietic stem-cell transplantation (allo-HCT), an early developed methodology for precision medicine, remains the only curative therapy for myelodysplastic syndromes (MDS). However, allo-HCT carries significant risks of morbidity and mortality due to relapse and transplant-related co...

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Bibliographic Details
Main Authors: Jing Dong, Michael T. Zimmermann, Neshatul Haque, Shahram Arsang-Jang, Wael Saber, Xiaowu Gai, Raul Urrutia
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Transplantation Reports
Subjects:
mtDNA
Structural genomics
Allo-HCT
Online Access:http://www.sciencedirect.com/science/article/pii/S2451959625000010

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http://www.sciencedirect.com/science/article/pii/S2451959625000010

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