Hydrogen Sulfide Ameliorates Angiotensin II-Induced Atrial Fibrosis Progression to Atrial Fibrillation Through Inhibition of the Warburg Effect and Endoplasmic Reticulum Stress

Hydrogen Sulfide Ameliorates Angiotensin II-Induced Atrial Fibrosis Progression to Atrial Fibrillation Through Inhibition of the Warburg Effect and Endoplasmic Reticulum Stress

Atrial fibrosis is the basis for the occurrence and development of atrial fibrillation (AF) and is closely related to the Warburg effect, endoplasmic reticulum stress (ERS) and mitochondrion dysfunctions-induced cardiomyocyte apoptosis. Hydrogen sulfide (H2S) is a gaseous signalling molecule with ca...

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Bibliographic Details
Main Authors: Heng-Jing Hu, Xiu-Heng Wang, Yao Liu, Tian-Qing Zhang, Zheng-Rong Chen, Chi Zhang, Zhi-Han Tang, Shun-Lin Qu, Hui-Fang Tang, Zhi-Sheng Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
atrial fibrosis
atrial fibrillation
angiotensin II
endoplasmic reticulum stress
hydrogen sulfide
warburg effect
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.690371/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.690371/full

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