The protective effect of Bifidobacterium bifidum G9-1 against mucus degradation by Akkermansia muciniphila following small intestine injury caused by a proton pump inhibitor and aspirin

The protective effect of Bifidobacterium bifidum G9-1 against mucus degradation by Akkermansia muciniphila following small intestine injury caused by a proton pump inhibitor and aspirin

Background Proton pump inhibitors (PPIs) can alleviate upper gastrointestinal injury but paradoxically exacerbate aspirin (ASA)-induced small intestine injury. In this study, our goal was to simulate this exacerbation by developing an appropriate animal model, which may help in establishing treatmen...

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Bibliographic Details
Main Authors: Tsutomu Yoshihara, Yosuke Oikawa, Takayuki Kato, Takaomi Kessoku, Takashi Kobayashi, Shingo Kato, Noboru Misawa, Keiichi Ashikari, Akiko Fuyuki, Hidenori Ohkubo, Takuma Higurashi, Yoko Tateishi, Yoshiki Tanaka, Shunji Nakajima, Hiroshi Ohno, Koichiro Wada, Atsushi Nakajima
Format: Article
Language:English
Published: Taylor & Francis Group 2020-09-01
Series:Gut Microbes
Subjects:
proton pump inhibitor
aspirin
intestinal injury
bifidobacterium bifidum g9-1
akkermansia muciniphila
Online Access:http://dx.doi.org/10.1080/19490976.2020.1758290

Internet

http://dx.doi.org/10.1080/19490976.2020.1758290

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